Observe hypertension response to sildenafil in sufferers getting concurrent blood pressure level decreasing therapy.
bisoprolol improves effects of sildenafil by additive vasodilation. Use Warning/Keep an eye on. Sildenafil has systemic vasodilatory Houses and should more lower blood pressure in individuals using antihypertensive prescription drugs.
These are typically not many of the possible side effects of Viagra® and generic Viagra®. For more information, request your Health care provider or pharmacist.
Nitrate medicines. See "What's the most important data I should really know about sildenafil tablets? "
In healthy volunteers, plasma concentrations of the metabolite are around 40% of Individuals observed for sildenafil, so that the metabolite accounts for about 20% of sildenafil's pharmacologic effects. In individuals with PAH, nevertheless, the ratio on the metabolite to sildenafil is better. Both equally sildenafil as well as the active metabolite have terminal 50 %-life of about 4 several hours.
mavorixafor will enhance the amount or effect of sildenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Keep an eye on for adverse effects of sensitive CYP3A4 substrates if coadministered with mavorixafor (a weak CYP3A4 inhibitor).
यहां दी गई जानकारी साल्ट (सामग्री) पर आधारित है. इसके उपयोग और साइड इफेक्ट्स एक से दूसरे व्यक्ति पर भिन्न हो सकते है.
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fosaprepitant will boost the level or effect of sildenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Contraindicated. Coadministration contraindicated if sildenafil used for pulmonary arterical hypertension. Lessen sildenafil dose if utilized for erectile dysfunction.
Stiripentol is often a CYP3A4 inhibitor and inducer. Keep an eye on CYP3A4 substrates coadministered with stiripentol for enhanced or reduced effects. CYP3A4 substrates might demand dosage adjustment.
Watch Carefully (one)idelalisib will improve the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
acebutolol improves effects of sildenafil by additive vasodilation. Use Warning/Check. Sildenafil has systemic vasodilatory Attributes and should even further decrease hypertension in patients having antihypertensive remedies.